The charity says it's busy at a number of its care centres due to the volume of animals it's looking after.
It says it recently removed 10 kittens from a house in County Wicklow as the cats were breeding out of control.
The ISPCA asks for a donation fee of 60 euro to help cover veterinary costs.
Wicklow Faces Ongoing Flood Risks Despite Improvement in Weather Conditions
Wicklow Coastal Areas Best Avoided During Status Orange Alert
*UPDATE* Wicklow Orange Rain Warning Change As Flood Risk Remains High
Wicklow Flood Relief: Support Available for Businesses and Community Groups
UPDATE: Ban On Scrambler Bikes In Public Spaces Agreed By Cabinet