The charity says it's busy at a number of its care centres due to the volume of animals it's looking after.
It says it recently removed 10 kittens from a house in County Wicklow as the cats were breeding out of control.
The ISPCA asks for a donation fee of 60 euro to help cover veterinary costs.
Wicklow Gardaí Urge Extreme Caution On Road Safety This Christmas
Wicklow Coastguard Urges Safety First for Christmas and New Year Dips
Wicklow Commuters To Benefit As New DART Trains Set To Transform Coastal Commuting
Shaping the Future of Newtownmountkennedy: A Town Team’s Vision for Growth and Community
North Wicklow GP Advice As Flu Season Hits Hard Locally