The site has been lying idle since 2006 when Dell relocated to Cherrywood with the loss of 1,000 local jobs.
A slightly altered version of the new design will see a mix of residential and commercial properties including a nursing home and an office block.
Some locals had expressed concerns the planned 4 storeys would overlook their homes and restrict their views of Bray Head.
The new design will stretch to only 3 storeys in the north and east of the site.
Fianna Fáil Health Spokesperson Wicklow TD Stephen Donnelly has welcomed the first phase of the planning application.
Gardaí Warn Of Rising Email And Retail Scams In Wicklow
Minister Meets Arklow Merck Staff as Closure Talks Continue
Bray Teen’s Bail Revoked Over Breaches Linked to Local Man’s Death
Devastating Blow As 100 Jobs To Go As Merck Life Science Plant Operations To Close In Arklow
178 Wicklow Homeowners Have Successfully Tapped Into The Vacant Property Refurbishment Grant